What is Triple-Negative Breast Cancer and Bullet Points You Must Know
Author: ichhori.com
Published: March 2022
Introduction
Triple-negative breast cancer (TNBC) is a less common but aggressive form of breast cancer. It is called "triple-negative" because it does not have the three common receptors known to fuel most breast cancer growth—estrogen, progesterone, and the HER2 protein.
What Makes It Different?
- TNBC does not respond to hormonal therapy (like Tamoxifen) or therapies that target HER2 receptors.
- It typically affects younger women, especially those under 50.
- More common among African-American women and those with BRCA1 gene mutations.
- It tends to grow and spread faster than other types of breast cancer.
Symptoms
- Lump in the breast or underarm
- Change in breast size or shape
- Nipple discharge or inversion
- Breast pain or tenderness
Diagnosis
Diagnosis is made through imaging tests (mammogram, ultrasound, MRI) and confirmed via biopsy and receptor testing. The cancer is classified as triple-negative if all three receptors test negative.
Treatment Options
- Chemotherapy: Main treatment since hormone therapy and HER2-targeted therapy don’t work.
- Surgery: Lumpectomy or mastectomy may be performed depending on tumor size and spread.
- Radiation Therapy: Often used after surgery to kill remaining cancer cells.
- Immunotherapy: A newer option for advanced TNBC cases, often combined with chemo.
Prognosis
The prognosis for TNBC is generally poorer compared to other breast cancers due to its aggressive nature. However, early detection and appropriate treatment can improve survival rates.
Prevention & Awareness
- Regular self-exams and clinical screenings
- Genetic testing if there's a family history
- Healthy lifestyle: balanced diet, exercise, avoiding smoking and alcohol
Conclusion
Triple-negative breast cancer is a challenging form of cancer, but with growing research and better treatment options, there is hope. Awareness, early diagnosis, and proactive healthcare are key to managing TNBC effectively.
Source: ichhori.com
